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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Therapeutic Pipeline Program, 2016
    Effect of HDAC Inhibition in Models of Parkinson's Disease

    Study Rationale:
    Numerous publications have linked the family of epigenetic enzymes known as HDACs (histone deactylases) to the underlying pathology of Parkinson's. This study will test the efficacy of...

  • Rapid Response Innovation Awards, 2007
    Everyday Action Impairment in People with Parkinson's Disease Dementia/Dementia with Lewy Bodies

    Objective/Rationale:
    Parkinson’s disease (PD) and Parkinson’s Disease Dementia/Dementia with Lewy Bodies (PDD/DLB) have been associated with cognitive deficits and everyday action impairment (EAI; e.g...

  • Biomarkers, 2011
    Identifying Peripheral Inflammatory Markers for Parkinson's Disease with Dementia (PDD)

    Objective/Rationale:
    Patients with Parkinson’s disease (PD) are at a 5.9 times greater risk of developing dementia than the normal population. The identification of sensitive molecular and cellular...

  • Rapid Response Innovation Awards, 2008
    Effects of noradrenergic or serotoninergic system lesions combined with NS lesions on rodent models of 'non-motor'-like symptoms

    Objective/Rationale:
    Parkinson’s disease is widely attributed to neuropathy of dopaminergic neurones in the nigrostriatal (NS) pathway. Degeneration of noradrenergic and serotonergic neurones in the...

  • Research Grant, 2023
    Exploiting a Novel Mechanism for Gene Regulation to Develop Innovative, Targeted Therapies for Parkinson’s Disease

    Study Rationale: Neurodegenerative disorders such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) are associated with a variety of disease-causing mutations and genetic variants. In addition...

  • Therapeutic Pipeline Program, 2016
    Highly Selective M1 Muscarinic Receptor Positive Allosteric Modulators for the Treatment of Parkinson's Dementia

    Study Rationale:                             
    Up to 80% of individuals with Parkinson’s develop Parkinson’s disease dementia (PDD), which is characterized by a progressive loss of memory and a decline...

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Our funding programs support basic, translational and clinical research from academia and industry.

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