The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Parkinson’s Disease Therapeutics Pipeline Program, 2024First-in-human Phase 1a Study to Assess Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending doses of SB-0110 after Oral Administration in Healthy Subjects
Study Rationale: Although levodopa is an effective treatment for Parkinson’s disease (PD), it has a debilitating on-target side effect of dyskinesia. An optimal PD therapy would selectively activate...
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Freezing of Gait Program, 2024Use of Neuromodulation to Relieve Gait Freezing in Parkinson’s Disease
Study Rationale: Almost all individuals with Parkinson’s disease (PD) develop episodes of freezing of gait, which is a sudden inability to take a step while walking. Gait freezing can cause falls that...
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2024Study of Multiple Air Pollutants in Parkinson’s Disease (MAP-PD)
Study Rationale: Chemicals in our environment, including some air pollutants, likely contribute to the development of Parkinson’s disease (PD). However, relatively few chemicals have been identified...
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2024Investigating the Effects of Pesticide Exposure on Immune System Function in Parkinson’s Disease
Study Rationale: Although it is well known that exposure to environmental substances, including pesticides, contributes considerably to Parkinson’s disease (PD), the mechanisms are largely unexplored...
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Research Grant, 2024Qualitative Evaluation of Draft Questionnaires for Patient-reported Outcome Measures of Non-motor Symptoms in Early-stage Parkinson's Disease
Study Rationale: This project seeks to address an unmet need for fit-for-purpose, clinical outcome assessments for early-stage Parkinson’s disease (PD) to be used in clinical trials to capture the...
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2024Strengthening Evidence-based Regulatory Decision-making to Address the Impact of Pesticides on Parkinson's Disease Risk
Study Rationale: Parkinson's disease (PD) is a growing global health concern, and recent research suggests that exposure to certain toxic chemicals, such as pesticides, may contribute to its...
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Our funding programs support basic, translational and clinical research from academia and industry.