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MJFF Publications

The Michael J. Fox Foundation continually strives to communicate our scientific progress with the research community — through posters and presentations at meetings, in peer-reviewed scientific publications and with white paper reports.

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    MJFF Alpha-Synuclein Mouse Comparison Study

    MJFF funded a study to compare multiple common alpha-synuclein mouse models to understand their PD-related phenotypes at 4, 8, and 12 months of age. Lines include Thy-1 aSyn Line 15 Tg (MJFF), Thy-1…
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    Analysis of Genetic Mutations in the BioFIND Cohort

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    Overview of GI Dysfunction Models

    Gastrointestinal (GI) dysfunction is a common issue in Parkinson’s disease (PD). Symptoms including dysphagia, bloating, and constipation, with constipation often reported decades before motor…
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    Overview of Parkin Models

    Mutations in the parkin gene cause autosomal recessive, young onset Parkinson’s disease (PD). The PD-linked mutations in parkin lead to loss of expression/function of the Parkin protein, an E3…
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    Overview of PINK1 Models

    Mutations in the PTEN-induced kinase 1 (PINK1)  gene cause autosomal recessive, young onset Parkinson’s disease (PD). The PD-linked mutations in PINK1 lead to loss of expression/function of the…
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    Overview of Mitochondrial Dysfunction Models

    Mitochondrial function is a pathway of great interest for Parkinson’s disease (PD) research and therapeutic development given the dysfunction that has been observed in idiopathic patients, patients…
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    Overview of Inflammation Models

    Inflammation is a pathway of great interest for Parkinson’s disease (PD) research and therapeutic development given evidence of innate and adaptive immune changes in PD patients. Inflammation is also…
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Articles authored by Rachel Dolhun, MD, a movement disorder specialist on staff at MJFF, offer a practical review of topics related to Parkinson's disease for practicing clinicians.

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Female researcher pipetting in lab.

Breaking Research Updates

Read the latest developments in the field’s understanding and treatment of Parkinson’s disease.

Read Research News
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