Prof. Armin Giese is chief scientific officer of MODAG. Previously, he was acting head of department at the Center for Neuropathology and Prion Research (ZNP) at the Ludwig Maximilian University of Munich and acting head of the German Reference Center for Neurodegenerative Diseases (DGNN). He holds a Bachelor of Science from the University College London, medical licenses from the University of Kiel and a Doctor of Medicine from the University of Göttingen. Dr. Giese is a board-certified neuropathologist. He has published more than 150 scientific publications that have been cited more than 19,000 times. His scientific work focuses on the role of protein aggregation in neurodegenerative diseases. He developed new high-throughput methods for the detection of protein oligomers and for the screening of aggregation inhibitors based on single particle spectroscopy. He identified novel aggregation inhibitors such as anle138b and PET tracer candidates. He co-founded MODAG in 2013.
Associated Grants
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Anle138b Clinical Phase 1 Studies: Food Effect, Safety and Tolerability as well as Pharmacokinetics in Parkinson´s Disease Patients
2020
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Pre-clinical Development of the Oligomer Modulator anle138b and Establishment of a Novel Seeding-based Biomarker
2015
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Evaluation of the Oligomer Modulator anle138b in a Seeding-based Model of Parkinson’s Disease
2014