Claudia Manzoni has worked on complex degenerative disorders of the brain, particularly Parkinson’s disease (PD) and dementias, for the past 10 years. The first goal of her research is to translate genetic results into an understanding of the molecular pathways involved in disease. Therefore, her research sits at the interface between genetics and functional biology and is aimed at easing the bidirectional flow of information between genetics and functional models through bioinformatics and systems biology pipelines for -omics data processing. The second goal of her research is to identify the contribution of risk factors for complex neurodegenerative disorders at an individual level. Therefore, she is interested in developing computational pipelines involving machine learning methods to model the personal risk of complex neurodegenerations.