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Parkinson’s Disease Therapeutics Conference Showcases Progress Toward Better Treatments
… known to be highly heterogenous (different for everyone). Multiple speakers at the conference talked about better … cells in the brain. However, another neurotransmitter system, the cholinergic system, has also been found to …
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High-throughput LRRK2 Ubiquitination Assay
… mechanism for LRRK2. This work will create a measurable system to detect the phosphorylation/ubiquitination of LRRK2 … cycle of LRRK2 modification. Project Goal: Cellular systems are ideal to study the molecular players in a … can be adapted to a multi-well format to enable testing of multiple regulators of LRRK2 phosphorylation at once. Study …
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Development of ALK4290 as a Novel Parkinson's Therapeutic
… Study Rationale: There is clear evidence that the immune system plays an important role in the development and … of pathologic inflammation, with potential effects on multiple symptoms associated with Parkinson's disease. …
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Use of an Angiotensin-(1-7) Glycopeptide, to Treat Dementia in Parkinson's Disease
… alpha-synuclein) via its effect on the Renin Angiotensin System in the brain, a system that is associated with … followed by other cellular and molecular analyses in multiple brain regions to understand how PNA5 alters …
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Effects of IL-10 on Neurodegeneration in Mutant Alpha-Synuclein Transgenic Models
… therapeutic approaches that target the immune system in PD. Project Description: In trying to … we would suggest that this study also open the door to multiple lines of therapeutically oriented research to …
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The Michael J. Fox Foundation Is Hiring
September 13, 2016
… organized, detail-oriented project manager to support multiple research initiatives focused on MJFF's clinical … and a Cisco Administrator to maintain computer systems and networks aiming for the highest functionality. …