The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2010Ghrelin - a Peripheral, Preclinical Biomarker for Parkinson's Disease
Promising Outcomes of Original Grant:
In our original grant we investigated serum concentrations of the hormone ghrelin in the fasting state and at different time points after a standardized test meal... -
Biomarkers, 2010Prospective Validation of Risk Markers for the Development of Parkinson’s Disease
Promising Outcomes of Original Grant:
As Parkinson’s disease is diagnosed when already a number of neurons have degenerated the PRIPS cohort consisting of 1847 healthy subjects older than 50 years was... -
Rapid Response Innovation Awards, 2009Enhanced Delivery of Viral Vectors to Striatum with Solid-State Biodegradable Matrices
Objective/Rationale:
When treating patients with neurological disorders, physicians frequently administer drugs through a small plastic tube or needle placed into the target area of the brain... -
Clinical Intervention Awards, 2009NIC-PD Trial to Assess the Disease-modifying Potential of Transdermal Nicotine in Early Parkinson's Disease
Objective/Rationale:
No drugs are available that can slow or stop the progression of Parkinson’s disease (PD). Nicotine is a promising substance for this purpose. Firstly, epidemiological studies... -
Understanding LRRK2 Biology, 2009Characterization of LRRK2 Cellular and Signaling Pathways
Objective/Rationale:
Mutations in LRRK2 are thus far the most common known cause of late-onset Parkinson’s disease (PD). The most prevalent LRRK2 mutation G2019S has been shown to stimulate LRRK2... -
Understanding LRRK2 Biology, 2009Elucidating the Function and Downstream Targets of LRRK2
Objective/Rationale:
One of the most exciting recent advances in PD research is that mutations within the gene coding for a protein of unknown function, LRRK2, predispose people to PD. Since a number...
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Our funding programs support basic, translational and clinical research from academia and industry.