The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2013Control of the Nigrostriatal Pathway by the Tail of the Ventral Tegmental Area
Objective/Rationale:
Neuroanatomical inputs to the substantia nigra pars compacta (SNc) modulate the activity of dopamine neurons and could influence the symptoms of Parkinson’s disease. A new brain... -
Biosample and Tissue Resource, 2013Assessing Glucocerebrosidase in Sporadic Parkinson’s Disease
Objective/Rationale:
Mutations in the glucocerebrosidase (GBA) gene are the most common genetic risk factor for Parkinson’s disease (PD). These mutations are present in approximately seven... -
Research Grant, 2013Exosome/Microvesicle Release from LRRK2 Mutant iPSC-derived Neural Cells
Objective/Rationale:
Exosomes/microvesicles are small vesicles that are shed from the cell membrane and are known to play a role in communication between cells. Exosomes/microvesicles... -
Research Grant, 2013Evaluation of Alpha-synuclein Immunohistochemical Methods for the Detection of Lewy-type Synucleinopathy in Gastrointestinal Biopsies
Objective/Rationale:
Lewy bodies, which consist mainly of aggregated protein alpha-synuclein, are a pathological hallmark of Parkinson’s disease (PD). Lewy bodies in the enteric nerves... -
Biosample and Tissue Resource, 2013Measuring LRRK2 Levels and Activity in Sporadic Parkinson’s Disease
Objective/Rationale:
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been linked to Parkinson’s disease (PD). The most prevalent mutation, G2019S, results in increased... -
Parkin Biology, 2013Identification of De-ubiquitinating Enzymes for Parkin-mediated Mitophagy
Objective/Rationale:
There is an urgent need to understand the cell processes that contribute to the cause of Parkinson’s disease. Parkin is an active enzyme within the cell that provides...
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Our funding programs support basic, translational and clinical research from academia and industry.