The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Lysosomal Biomarkers Program, 2023Validating Measurements of Peripheral GCase Longitudinally Under Clinical Trial Conditions
Study Rationale: An enzyme known as GCase is a key protein that stops working properly in people with Parkinson’s disease (PD). However, determining exactly how impaired the enzyme’s activity might...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Effect of SAR-CoV-2 on Experimental Parkinsonism in a Preclinical Model of Parkinson’s Disease
Study Rationale: Approximately 16.5 million people have been infected with the SARS-CoV2 virus. While primarily a respiratory virus, clinical observations indicate that in many cases, infection is...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Targeting the Blood-brain Immune Axis to Prevent Progression of Parkinson’s Disease
Study Rationale: Recent studies suggest that the barrier that separates the brain from the rest of the body, including the blood, might become dysfunctional over the course of Parkinson’s disease (PD)...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023SUPPLEMENT | Reducing Expression of the Gene for Alpha-synuclein in an Advanced Preclinical Model of Parkinson’s Disease
Study Rationale: Numerous genetic studies of families with parkinsonism and mutations in the alpha-synuclein gene suggest that an excess of alpha-synuclein leads to neurodegeneration and Parkinson’s...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Examining a Novel GCase Activator in Neurons Derived from People with Parkinson’s Disease
Study Rationale: Decreased function of the lysosomal enzyme GCase is associated with Parkinson’s disease (PD). We discovered that LIMP-2, the protein that transports GCase to the lysosome, also...
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Research Grant, 2023(SUPPLEMENT) The Foundational Data Initiative
Study Rationale: This project aims to produce foundational data that will provide a resource for understanding the molecular basis of Parkinson’s disease (PD). The work, conducted in cells collected...
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Our funding programs support basic, translational and clinical research from academia and industry.