The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Aligning Science Across Parkinson's, 2023(Supplement) Exploring the Mechanisms by which Co-pathologies Drive Neuroinflammation and Progression in Parkinson’s Disease
Study Rationale: Although Parkinson’s disease (PD) is considered a synucleinopathy, the clinical progression of PD is driven by additional pathological proteins such as tau and beta amyloid. We...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Surviving on Borrowed Energy: Using Mitochondrial Transfer to Treat Parkinson’s Disease
Study Rationale: By the time the symptoms of Parkinson’s disease (PD) appear, many of the brain cells that produce the chemical dopamine have already died. This loss of dopamine-making cells leads to...
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Data-Driven Subtyping and Stratification Program, 2023Using Machine Learning on Longitudinal Data from Multiple Cohorts to Determine Biological Subtypes and Prediction Scores for Parkinson’s Disease
Study Rationale: We used to think of Parkinson's disease (PD) as a single disorder. However, individuals with PD can be very different in terms of their clinical characteristics and the biological...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Using a Virally Encoded, Single-chain Antibody as a Noninvasive Gene Therapy for Parkinson’s Disease
Study Rationale: The main pathological hallmarks of Parkinson’s disease (PD) are the degeneration of dopamine-producing brain cells and the accumulation of protein aggregates containing misfolded...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023(Supplement) Cellular Brain Repair for Parkinson’s Disease: Preclinical Therapeutic Validation of Biomaterial-supported Cell Transplants Coupled with Immunosuppression
Study Rationale: Although transplantation of stem cell-derived brain cells is a promising therapeutic approach for Parkinson’s disease (PD), only a small fraction of the cells that are transplanted...
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Data-Driven Subtyping and Stratification Program, 2023Identifying Distinct Patterns in Parkinson’s Disease Progression Using Integrative, Data-driven Subtype Analysis
Study Rationale: Parkinson’s disease (PD) is associated with diverse motor and non-motor manifestation that progress gradually over time. Although this progression differs from individual to...
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Our funding programs support basic, translational and clinical research from academia and industry.