Funded Studies

Study Rationale: Many people with Parkinson’s disease (PD) suffer from pain that is not managed well by existing therapies. We believe the ineffectiveness of these treatment strategies may be due to a...

Study Rationale: Over the past two decades, we have developed a therapy that restores walking after paralysis due to a spinal cord injury. This therapy uses an implanted neurostimulation prosthesis to...

Study Rationale: Although Parkinson’s disease (PD) is considered a synucleinopathy, the clinical progression of PD is driven by additional pathological proteins such as tau and beta amyloid. We...

Study Rationale: By the time the symptoms of Parkinson’s disease (PD) appear, many of the brain cells that produce the chemical dopamine have already died. This loss of dopamine-making cells leads to...

Study Rationale: We used to think of Parkinson's disease (PD) as a single disorder. However, individuals with PD can be very different in terms of their clinical characteristics and the biological...

Study Rationale: The main pathological hallmarks of Parkinson’s disease (PD) are the degeneration of dopamine-producing brain cells and the accumulation of protein aggregates containing misfolded...