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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2022
    Examining the Role of Cannabinoid Receptor 2 in Inflammatory Responses Triggered by Alpha-synuclein

    Study Rationale: There is growing interest in the anti-inflammatory properties of cannabis-related compounds as a potential therapy for Parkinson’s disease (PD). Cannabis acts on cannabinoid receptors...

  • Research Grant, 2022
    Using Integrated Biomarkers of Prodromal Parkinson’s Disease to Assess the Efficacy of Exercise Intervention in the Earliest Phase of Disease

    Study Rationale: In individuals with Parkinson’s disease (PD), the pathological processes are already advanced by the time a clinical diagnosis is made. This delay contributes to the difficulty in...

  • Research Grant, 2022
    Restoring the Blood-brain Barrier to Prevent Dissemination of Alpha-synuclein and Progression of Parkinson’s Disease

    Study Rationale: The cells of the brain are physically separated from the rest of the body by the blood-brain barrier, a network of blood vessels that restricts transfer of materials from the...

  • Research Grant, 2022
    Using the Emergence of New Symptoms as a Measure for Parkinson’s Disease Progression in Clinical Trials

    Study Rationale: Studies suggest that as Parkinson’s disease (PD) progresses, new areas of the brain fall prey to PD pathology. If this is the case, PD progression may be best assessed by tracking the...

  • Research Grant, 2022
    Perspective and Consensus on Prevention Planning for Parkinson’s Disease

    Study Rationale: In October 2022, a conference on “Planning for Prevention of Parkinson's: A trial design forum” gathered a broad range of stakeholders interested in preventing Parkinson’s disease (PD...

  • Accelerating the Translation of Parkinson's Disease Therapies, 2022
    Testing Small Molecules that Activate Removal of Cellular Debris for the Treatment of Parkinson’s Disease

    Study Rationale:
    People with Parkinson’s disease (PD) exhibit a diminished ability to remove cellular trash — including old and damaged molecules and organelles — from the brain. This impairment is...

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