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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2018
    Evaluation and Comparison of Existing Tests for Alpha-synuclein

    Study Rationale:
    An increase in the levels of alpha-synuclein -- a sticky protein that clumps in the brains of people with Parkinson's disease (PD) -- has been directly linked to an increased risk of...

  • Research Grant, 2018
    Assessing the Effects of the Glucosylceramide Lipid on Protein Clumping

    Study Rationale:
    Changes (mutations) in the GBA1 gene cause Gaucher disease, a rare condition that causes fatty substances to build up and organs to swell, and increase the risk of Parkinson's disease...

  • Access to Data and Biospecimens, 2018
    A New Test for Rapid and Ultra-Sensitive Detection of Hallmarks of Parkinson's Disease in Cerebrospinal Fluid

    Study Rationale:
    The diagnosis and treatment of Parkinson's disease (PD) would be aided by the availability of direct and highly sensitive tests for the abnormal clumps of protein alpha-synuclein...

  • Access to Data and Biospecimens, 2018
    Discovery and Verification of Parkinson's Disease Biomarkers

    Study Rationale:
    The identification, development and use of Parkinson's disease (PD) biomarkers -- objective measures of disease -- remains a priority for researchers searching for a cure. Using a...

  • Alpha-Synuclein Biology and Therapies, 2018
    Antisense Oligonucleotides as Drug Candidates for Alpha-Synuclein-Linked Diseases

    Study Rationale:
    The goal of this project is to find drugs that target alpha-synuclein, a key protein in Parkinson's disease (PD). We will design and test second-generation antisense oligonucleotides...

  • Research Grant, 2018
    Parkin as a Protection Against Mitochondrial Stress

    Promising Outcomes of Original Grant:
    Parkin is one of the key proteins linked to Parkinson's disease (PD). Previously, we examined if enhanced function of parkin changes the composition and renewal of...

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