The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2014Creating Dopaminergic Neurons in the Adult Brain
Study Rationale:
Loss of dopaminergic neurons is seen in Parkinson’s disease, and transplantation of these neurons can greatly ease symptoms. However, several major drawbacks are associated with... -
Rapid Response Innovation Awards, 2014Effect of Dietary Ketosis On Alpha-Synuclein Accumulation
Study Rationale:
A key feature of Parkinson’s disease is abnormal accumulation of the protein alpha-synuclein. Production of organic compounds called ketones is a normal metabolic process that occurs... -
Rapid Response Innovation Awards, 2014D-512: a Novel, Multifunctional D2/D3 Receptor Agonist for the Treatment of Parkinson’s Disease
Study Rationale:
New drugs for the treatment of Parkinson’s disease (PD) that reduce symptoms and protect remaining neurons are desperately needed. This work examines a novel... -
Rapid Response Innovation Awards, 2014Levodopa Versus Dopamine Agonist after Deep Brain Stimulation in Parkinson's Disease
Study Rationale:
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established treatment for patients with advanced Parkinson's disease (PD). STN DBS improves motor... -
Resource: Utilizing DATATOP Biospecimens, 2014Circulating microRNAs as Progression Biomarkers for Parkinson's Disease
Promising Outcomes of Original Grant:
Our earlier study tested whether Parkinson’s disease (PD)-specific microRNAs in blood can be used to: (a) monitor disease development and (b) separate patients... -
Access to Data and Biospecimens, 2014BDNF Polymorphism and Parkinson’s Disease Progression in DATATOP
Study Rationale:
A relatively common mutation in the brain derived neurotrophic factor (BDNF) gene exists in the human population. Neurotrophic factors are like brain fertilizers that help neurons grow...
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Our funding programs support basic, translational and clinical research from academia and industry.