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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Access to Data and Biospecimens, 2014
    Analysis of Circulating Brain-Enriched microRNA as Biomarkers for Parkinson’s Disease

    Study Rationale:                   
    Early detection of neurodegenerative diseases can lead to more effective therapeutic intervention. DiamiR proposes a diagnostic approach based on analysis of...

  • Research Grant, 2013
    Virtual Research Visits

    Objective/Rationale:             
    The Michael J. Fox Foundation’s Fox Trial Finder is designed to facilitate and increase the participation of individuals with Parkinson’s disease in clinical trials...

  • Rapid Response Innovation Awards, 2010
    Increasing Endogenous Neurogenesis Using Neurosteroids: A Novel Therapeutic Strategy to Treat Parkinson's Disease

    Objective/Rationale
    We will test a locally produced brain chemical that increases the generation of new neurons to replace the damaged neurons in Parkinson disease (PD). The production of this...

  • Therapeutics Development Initiative, 2006
    Evaluation of the Neuroprotective Peptide NAPVSIPQ in Models of Parkinson's Disease

    Parkinson's disease is characterized by the selective loss of dopamine neurons, which leads to reduced control of voluntary locomotor activities. The cause of this degeneration is unknown; however...

  • Community Fast Track, 2004
    The role of nociceptin/orphanin FQ in regulation of motor behavior and induction of parkinsonism

    Nociceptin/orphanin FQ (N/OFQ) is an opioid-like neuropeptide discovered in the mid 90's, which activates a G-protein coupled receptor, the NOP receptor. N/OFQ and its receptor are diffusely expressed...

  • Postural Instability and Gait Disturbances, 2009
    The Role of White Matter Pathology in the Development of the Postural Instability and Gait Disturbance (PIGD) Type of Parkinson's Disease (PD)-1

    Objective/Rationale:
    It is not clear why a subset of patients with Parkinson's disease develop postural instability and gait disturbances (PIGD), while others do not. White matter (WM) changes that...

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