The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2009Effect of novel sirtuin inhibitors on alpha-synuclein toxicity in a Parkinson disease pre-clinical model
Objective/Rationale:
The objective of the proposed research is to test the ability of novel sirtuin inhibitors to protect against dopamine neuron toxicity in a pre-clinical model of Parkinson's... -
Rapid Response Innovation Awards, 2009Rational Vectors For PD
Objective/Rationale:
The project is hot on the trail of key suspect players in Parkinson’s disease. The output of an innovative screening process put forth a handful of candidate enzymes in a lower... -
Rapid Response Innovation Awards, 2009Crystal Structure of Alpha-Synuclein; Toward Rational Drug Design
Objective/Rationale: The alpha-synuclein is implicated in the pathogenesis of Parkinson’s disease. An aggregated form of synuclein containing many molecules has been proposed to interact destructively...
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Rapid Response Innovation Awards, 2009Probing the Neuroprotective Effects of Haploinsufficiency of RanBP2 in Neurotoxicant-induced Experimental Pre-clinical Models of Parkinson's Disease
Objective/Rationale:
A partial deficit in the level of Ran-binding protein-2 (RanBP2) confers neuroprotection to neurons upon aging and deleterious stimuli promoting oxidative stress, a stress... -
Rapid Response Innovation Awards, 2009Identification of Substrates and Development of a Cell Based Assay for LRRK2
Objective/Rationale:
Inherited mutations in a gene called LRRK2 have recently been discovered to cause Parkinson’s disease. The LRRK2 gene encodes an enzyme called a kinase, which is more active when... -
MJFF Research Grant, 2009PD Pre-clinical Model Repository
Objective/Rationale:
The Michael J. Fox Foundation (MJFF) is partnering with The Jackson Laboratory (JAX) to distribute pre-clinical models of Parkinson’s disease (PD). MJFF funding will allow JAX to...
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Our funding programs support basic, translational and clinical research from academia and industry.