The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2022Restoring the Blood-brain Barrier to Prevent Dissemination of Alpha-synuclein and Progression of Parkinson’s Disease
Study Rationale: The cells of the brain are physically separated from the rest of the body by the blood-brain barrier, a network of blood vessels that restricts transfer of materials from the...
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Research Grant, 2022Using the Emergence of New Symptoms as a Measure for Parkinson’s Disease Progression in Clinical Trials
Study Rationale: Studies suggest that as Parkinson’s disease (PD) progresses, new areas of the brain fall prey to PD pathology. If this is the case, PD progression may be best assessed by tracking the...
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Research Grant, 2022Perspective and Consensus on Prevention Planning for Parkinson’s Disease
Study Rationale: In October 2022, a conference on “Planning for Prevention of Parkinson's: A trial design forum” gathered a broad range of stakeholders interested in preventing Parkinson’s disease (PD...
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Accelerating the Translation of Parkinson's Disease Therapies, 2022Testing Small Molecules that Activate Removal of Cellular Debris for the Treatment of Parkinson’s Disease
Study Rationale:
People with Parkinson’s disease (PD) exhibit a diminished ability to remove cellular trash — including old and damaged molecules and organelles — from the brain. This impairment is... -
Research Grant, 2022LEARN-ATMP – Using the Patient Voice to Develop a Framework for Accessible ATMP Trials
Study Rationale: New therapies for Parkinson’s disease (PD) that involve the use of cells or genes — sometimes called advanced therapy medicinal products (ATMP) — are being developed and tested in...
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Accelerating the Translation of Parkinson's Disease Therapies, 2022Esya PD360: A Multi-parametric Platform for Establishing a Novel Lysosome-based Biomarker and Identifying Therapeutic Interventions for Parkinson’s Disease
Study Rationale: Lysosomes are sub-cellular compartments responsible for clearing proteins that are prone to aggregation, a process called autophagy. Dysfunctional lysosomes with increased acidity and...
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Our funding programs support basic, translational and clinical research from academia and industry.