The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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LRRK2, 2011Neuropathological tissue collection in LRRK2 Mutant carriers with and without PD
Objective/Rationale:
Neuropathological studies have been vital in Parkinson’s disease (PD) research. The gold-standard diagnosis of PD is confirmed at autopsy. In addition, information on key proteins... -
MJFF Research Grant, 2011Generation of LRRK2 Lentiviral Vectors
Objective/Rationale:
Overexpression of LRRK2 in mammalian cells, either transient or as stable cell lines, has proven cumbersome and quite inefficient. This can be partly attributed to the large size... -
Research Grant, 2011LRRK2 Effects on Neural Differentiation (Supplement 1)
Promising Outcomes of Original Grant:
Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) account for up to 13% of familial Parkinson's disease (PD) patients. One widely held... -
Rapid Response Innovation Awards, 2011Assessing the Therapeutic Potential of iDA Neuronal Cells in Autologous Strategy
Objective/Rationale:
We have shown recently that three transcription factors can promote the conversion of skin fibroblasts into induced dopaminergic neuronal (iDAN) cells with remarkable functional... -
Target Validation, 2011Targeting Beta-arrestin Signaling in the Treatment of Parkinson's Disease
Objective/Rationale:
Beta-arrestins were originally identified as proteins that attenuate the signaling function of the large class of receptors to which dopamine receptors belong. However, recently... -
Defining Cognitive Phenotypes of Parkinson's Disease, 2011Cognitive Phenotypes in Parkinson's Disease: Anatomical and Functional Correlates
Objective/Rationale:
Cognitive impairment with and without dementia is frequent in Parkinson's disease (PD). However, there is a high heterogeneity in the clinical presentation of these cognitive...
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Our funding programs support basic, translational and clinical research from academia and industry.