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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Novel Approaches to Drug Discovery, 2010
    Optimizing Metalloporphryins for Clinical Development Supplement

    Promising Outcomes of Original Grant:
    The overall goal of this ongoing proposal is to determine if a newly developed series of metalloporphyrins designed to penetrate blood brain barrier shows promise...

  • MJFF Research Grant, 2010
    Technology for Clinicogenetic Studies of LRRK2 G2019S in Tunisia

    Objective/Rationale:
    We seek to create and enhance a secure database, accessible by collaborators with customizable, user-friendly, web-based entry for clinical, genetic and pedigree information. This...

  • MJFF Research Grant, 2010
    The Parkinson's Progression Markers Initiative (PPMI)

    Objective/Rationale:
    Currently there is no definitive diagnostic test for Parkinson’s disease (PD) in a live patient, and no way to track disease progression on a biological level. These gaps have...

  • Rapid Response Innovation Awards, 2010
    Testing Whether Alpha-Synuclein is Modified by 4-hydroxy-2-nonenal in the Human Brain

    Promising Outcomes of Original Grant:
    The major goal of our grant application was to test whether a protein known as alpha-synuclein becomes toxic to dopamine-secreting nerve cells when it is modified...

  • MJFF Research Grant, 2010
    The Role of LRRK2 in Neurotransmission

    Objective/Rationale: 
    Parkinson disease involves loss of the neurochemical dopamine, and many of the motor symptoms are attributed to a dopamine deficit in the brain region called the striatum. Recent...

  • Novel Approaches to Drug Discovery for Parkinson's Disease, 2010
    Cerium Oxide Nanoparticles in Treatment of Parkinson's Disease

    Promising Outcomes of Original Grant:
    In our 2009-2010 proposal, we hypothesized that pretreatment of a pre-clinical model with cerium oxide nanoparticles would be neuroprotective in the MPTP-pre...

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Our funding programs support basic, translational and clinical research from academia and industry.

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