To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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AAV2/5 CBh WT Alpha-Synuclein Plasmid
Viral transgene plasmid used in the AAV2/5 WT alpha-synuclein viral vector available through Charles River Labs (see viral vector section). This plasmid is available to non-profit and for-profit groups. RRID:Addgene_194244
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AAV1/2 empty vector control
Viral transgene plasmid used in the AAV empty vector control viral vector for the AAV A53T alpha-synuclein viral vector, both available through Charles River Labs (see viral vector section). This plasmid is available to non-profit and for-profit groups. RRID:Addgene_194243
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AAV1/2 A53T Alpha-Synuclein Plasmid
Viral transgene plasmid used in the AAV1/2 A53T alpha-synuclein viral vector available through Charles River Labs (see viral vector section). This plasmid is available to non-profit and for-profit groups. RRID:Addgene_194242
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AAV Human SNCA 3xmiR/GFP Plasmid
Viral transgene plasmid used in the AAV Human SNCA 3xmiR/GFP viral vector available through Charles River Labs (see viral vector section). This plasmid is available to non-profit groups only. RRID:Addgene_194247
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AAV Mouse SNCA 3xmiR/GFP Plasmid
Viral transgene plasmid used in the AAV Mouse SNCA 3xmiR/GFP viral vector available through Charles River Labs (see viral vector section). This plasmid is available to non-profit groups only. RRID:Addgene_194248
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Rab 8A Antibody
Mouse anti-Rab8A antibody that has undergone Fc species switching to develop mouse reagents from the original rabbit antibody (MJF-R22-79-3). The new chimeric antibody is approved for immunoblotting, immunoprecipitation, immunostaining, and flow cytometry and can be detected using Fc-specific secondary antibodies to mouse IgG.
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SNCAbow Mouse*
Mouse expressing either nuclear localized SNCAWT:TagBFP, SNCAA30P:mTFP1, or SNCAA53T:mKO2 in cre-expressing tissues of the offspring directed by CAG promoter followed by three pairs of orthogonal lox sites (LoxN, Lox2272, and LoxP), and the SNCAbow construct; all targeted into the Gt(ROSA)26Sor locus. Each α-synuclein sequence contains a C-terminal epitope tag: SNCAWT tagged with V5, SNCAA30P tagged with 3XHA, or SNCAA53T tagged with Myc. Model was generated and deposited by Rodger Liddle at Duke University Medical Center through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:037603
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RILPL1 Antibody
Mouse monoclonal antibody directed against total rodent/human RILPL1 protein. Suitable for immunoblot, immunoprecipitation, and immunocytochemistry experiments. This antibody is a chimeric mouse IgG2a version of the rabbit anti-RILPL1 antibody (MJF-R41-21, ab302492).
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic