To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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Full Length pS129 Alpha-Synuclein Protein
Phospho-S129 Alpha Synuclein semi-synthetic phosphomimetic protein generated by native chemical ligation of a recombinant peptide produced from E. coli and a synthtic peptide
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Total Rab 8 Antibody (Hu/Ms/Rt)
Rabbit monoclonal antibody directed against the human and rodent total Rab 8 protein. Suitable for immunoblot and immunoprecipitation experiments. This antibody epitope was mapped to C-terminus amino acids 190-196.
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LRRK2 T1348N Mouse
Mice expressing the T1348N mutant (GTPase-dead) form of LRRK2. RRID:IMSR_JAX:021829
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Alpha-Synuclein KO Mouse
Homozygous knockout of alpha-synuclein created by deletion of SNCA exons 1-4 in the C57BL/6N mouse strain. RRID:IMSR_JAX:016123
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Alpha-Synuclein pS129 Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 129 of alpha-synuclein.
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Lentiviral LRRK2 (G2019S/D1994A)
Lentiviral vector expressing LRRK2 mutated at residues G2019S and D1994A. Lentiviral eGFP available as a control in Reporter section.
Please note: This viral vector is not intended for in vivo use.
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LRRK2 Antibody (MJFF4)
Rabbit monoclonal antibody directed against wild-type LRRK2. The antibody was mapped to the LRR domain of LRRK2 (AA 1035-1239).
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Thy-1 Wild Type Human Alpha-Synuclein Mouse (Line 61)*
Transgenic mice expressing wild type human alpha-synuclein cDNA driven by the mouse Thy1 promoter. Model was developed by Eliezer Masliah and deposited by Robert Rissman at University of California San Diego, and made available through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:038796
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic