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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Target Advancement Program, 2016
    Targeting the Mitochondrial Unfolded Protein Response in Alpha-synuclein-induced Parkinson's Disease

    Study Rationale:
    The mitochondrial (powerhouse of the cell) unfolded protein response (mtUPR) is the first defense mechanism for maintaining proper quality of proteins within the mitochondria. Defects...

  • Research Grant, 2016
    Novel Quantification in Parkinson’s Disease Neurochemical Imaging

    Promising Outcomes of Original Grant:
    We hypothesized in the original funded grant that evaluation of texture and variability, beyond conventional averaging of voxel (element of space) intensities...

  • Research Grant, 2016
    Electrical Stimulation of the Brain as Parkinson's Disease Treatment

    Study Rationale:
    Depression is a common non-motor symptom associated with Parkinson's disease (PD), and impulse control disorders (ICDs) are behaviors that may arise with use of certain PD medications...

  • Research Grant, 2016
    Registry for the Advancement of Deep Brain Stimulation Therapy in Parkinson's Disease (RAD-PD)

    Study Rationale:
    Deep brain stimulation (DBS) is a surgical treatment for Parkinson's disease (PD) that may benefit those who experience motor complications, such as "off" periods and/or dyskinesia...

  • Access to Data and Biospecimens, 2016
    MicroRNAs as biomarkers of the prodromal stage of Parkinson disease’

    Study Rationale:

    MicroRNAs (miRNAs) are small regulatory RNAs controlling gene expression. We have recently reported reduced  miRNAs levels in serum from Parkinson disease (PD) patients, and also from...

  • Research Grant, 2016
    Parkinson's Disease Genetics Sequencing Consortium

    Study Rationale:
    The Parkinson's Disease Genetics Sequencing Consortium (PDGSC) was established following a National Institute of Neurological Disorders and Stroke workshop in June 2014 and brings...

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