Funded Studies

Study Rationale:                   
Over-activation of brain immune cells, called microglia, is associated with the degeneration that occurs in Parkinson’s disease. This suggests that brain...

Study Rationale:                   
Speech and voice disorders are common in people with Parkinson’s disease (PD) and adversely affect their communication and quality of life. Presently, Lee Silverman...

Study Rationale:
A major challenge in Parkinson’s treatment is the management of levodopa-induced dyskinesias. A promising approach is offered by non-invasive neuromodulation techniques. We recently...

Study Rationale:                   
The dopamine precursor levodopa is the gold-standard treatment for Parkinson’s disease. However, as PD progresses, serotonin neurons increasingly convert levodopa to...

Study Rationale:                   
During the rapid eye movement (REM) phase of sleep, when we dream, our voluntary muscles are paralyzed so that we would not act out our dreams. In REM sleep behavior...

Study Rationale:                
Long-term treatment for Parkinson’s with levodopa can cause dyskinesia or involuntary movements. Other drugs like anti-dopaminergics can cause similar abnormal...