The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2021Development of Small-molecule Inhibitors that Reduce the Aggregation of Tau for the Treatment of Parkinson’s Disease
Study Rationale: The aggregation of alpha-synuclein and tau converts these proteins from a biologically functional state into toxic, fibrous deposits in the brains of people with Parkinson’s disease...
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Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2021Development of Novel Brain-penetrant Inflammasome Inhibitors as Potential Therapeutics for Parkinson’s Disease
Study Rationale: The immune system displays an aberrant pattern of activity in the central nervous system of people with Parkinson’s disease (PD); this pattern includes activation of a danger-sensing...
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Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2021Development of a Small-molecule Inhibitor Targeting Intracellular Alpha-synuclein Pathology
Study Rationale: Parkinson’s disease (PD) and other devastating neurodegenerative diseases, including Dementia with Lewy bodies (DLB) and Multiple System Atrophy (MSA), are characterized by the...
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Fall 2021 RFP: Outcome Measures, 2021Use of Image-enhancement Techniques to Assess Anatomical Changes in Parkinson’s Disease
Study Rationale: Parkinson’s disease (PD) has several subtypes. Identification of these subtypes in individuals with PD is important for understanding disease progression, developing new therapies...
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Diversity, Equity and Inclusivity in Parkinson's research, 2021Study of Cognitive Differences in a South Asian Population with Parkinson’s Disease
Study Rationale: Research on Parkinson’s disease (PD) has focused mainly on White, affluent populations. Little is known about PD in people of color. East London is one of the most diverse parts of...
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, 2021Evaluating Patient-reported Outcome Assessment in Early Parkinson’s Disease
Study Rationale: There are currently no validated tools for assessing functional changes in people at the earliest clinical stages of Parkinson’s disease (PD). Available approaches lack sufficient...
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Our funding programs support basic, translational and clinical research from academia and industry.